UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D. C. 20549

                                  ------------

                                    FORM 8-K

                                 CURRENT REPORT
                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act Of 1934

                                 March 27, 2006
                Date of Report (Date of earliest event reported)

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                           ACURA PHARMACEUTICALS, INC.
               (Exact Name of Registrant as Specified in Charter)

           -----------------------------------------------------------

    State of New York                   1-10113               11-0853640
(State of Other Jurisdiction    (Commission File Number)    (I.R.S. Employer
    of Incorporation)                                     Identification Number)

                          616 N. North Court, Suite 120
                            Palatine, Illinois 60067
               (Address of principal executive offices) (Zip Code)

                                 (847) 705-7709
              (Registrant's telephone number, including area code)


Check the appropriate box below if the Form 8-K filing is intended to
simultaneously satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

[ ]   Written communications pursuant to Rule 425 under the Securities Act (17
      CFR 230.425)

[ ]   Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
      240.14a-12)

[ ]   Pre-commencement communications pursuant to Rule 14d-2(b) under the
      Exchange Act (17 CFR 240.14d- 2(b))

[ ]   Pre-commencement communications pursuant to Rule 13e-4(c) under the
      Exchange Act (17CFR 240.13e- 4(c))

Item 8.01 Other Events As disclosed in the Registrant's Form 8-K filed with the Commission on January 31, 2006, the Registrant borrowed $750,000 pursuant to a Loan Agreement dated as of January 31, 2006 with various lenders (the "Bridge Lenders"). The Loan Agreement also permitted additional loan advances to the Registrant. On March 27, 2006, the Bridge Lenders extended the Registrant an additional $750,000 in loans, pursuant to the Loan Agreement. Item 9.01 Financial Statements and Exhibits Exhibit Number Description - -------------- ----------- 99.1 Press Release dated March 27, 2006 Announcing Receipt of Interim Funding

SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized. ACURA PHARMACEUTICALS, INC. By: /s/ Peter Clemens Peter A. Clemens Senior Vice President & Chief Financial Officer Date: March 27, 2006

Exhibit Index Exhibit Number Description - -------------- ----------- 99.1 Press Release dated March 27, 2006 Announcing Receipt of Interim Funding

CONTACT: Acura Pharmaceuticals, Inc.,
Investor Relations, Peter A. Clemens, SVP & CFO   847-705-7709


                              FOR IMMEDIATE RELEASE

               ACURA PHARMACEUTICALS, INC. SECURES BRIDGE FUNDING

Palatine,  IL, March 27, 2006: Acura  Pharmaceuticals,  Inc. (OTC.BB-ACUR) today
announced it has secured gross  proceeds of $750,000 under a term loan agreement
(the  "Loan")  with  Essex  Woodlands  Health  Ventures  V, L.P.,  Care  Capital
Investments II, L.P., Care Capital Offshore Investments II, L.P., Galen Partners
III, L.P., Galen Partners  International  III, L.P. and Galen Employee Fund III,
L.P (collectively the "Bridge Lenders"). The Loan matures on June 1, 2006, bears
an  annual  interest  rate of 10%,  is  secured  by a lien on all  assets of the
Company and its subsidiary, and is senior to all other Company debt. The Company
will use utilize the net  proceeds  from the Loan to  continue  funding  product
development and licensing  activities  relating to OxyADF(TM)  tablets and other
product candidates  utilizing its Aversion(R)  Technology.  The Loan permits the
funding of additional  cash amounts  subject to agreement by the Company and the
Bridge Lenders. No assurance can be given,  however, that any additional funding
will be advanced to the Company under the terms of the Loan.

Cash Reserves Update

The Company estimates that its current cash reserves, including the net proceeds
from the Loan, will fund product  development and licensing  activities  through
mid May,  2006.  To  continue  operating  thereafter,  the  Company  must  raise
additional  financing or enter into  appropriate  collaboration  agreements with
third parties  providing  for cash payments to the Company.  No assurance can be
given that the Company will be successful in obtaining any such  financing or in
securing collaborative  agreements with third parties on acceptable terms, if at
all, or if secured, that such financing or collaborative agreements will provide
for payments to the Company  sufficient to continue funding  operations.  In the
absence of such financing or third-party collaborative  agreements,  the Company
will be required to scale back or terminate  operations  and/or seek  protection
under applicable bankruptcy laws.

About Acura Pharmaceuticals, Inc.

Acura  Pharmaceuticals,  Inc.,  together  with its  subsidiary,  is a  specialty
pharmaceutical   company   primarily   engaged  in  research,   development  and
manufacture of innovative abuse deterrent,  abuse resistant and tamper resistant
formulations  ("Aversion(R) Technology") intended for use in orally administered
opioid-containing pharmaceutical products.

Forward Looking Statements This press release contains "forward-looking statements" as defined in the Private Securities Litigation Reform Act of 1995. These statements are based on current expectations of future events. If underlying assumptions prove inaccurate or unknown risks or uncertainties materialize, actual results could vary materially from the Company's expectations and projections. The most significant of such risks and uncertainties include, but are not limited to, the Company's ability to secure additional financing to fund continued product development and operations, the Company's ability to enter into contractual arrangements with qualified pharmaceutical partners to license, develop and commercialize the Company's technology and product candidates, the Company's ability to avoid infringement of patents, trademarks and other proprietary rights or trade secrets of third parties and the challenges inherent in new product development, including obtaining regulatory approvals. You are encouraged to review other important risk factors relating to the Company on our web site at www.acurapharm.com under the link, "Company Risk Factors" and detailed in Company filings with the Securities and Exchange Commission. The Company is at development stage and may never have any products or technologies that generate revenue. Acura Pharmaceuticals, Inc. assumes no obligation to update any forward-looking statements as a result of new information or future events or developments. All Acura Pharmaceuticals, Inc. press releases may be reviewed at www.acurapharm.com.