Ownership Profile

Shareholder Breakdown
  Holders Values ($) % O/S Shares
Institution 37 17.35 60.40 7,146,736
Mutual Fund 12 0.64 1.96 232,180

Institutional Shareholder Rotation
  Holders Values Change ($) % O/S Shares Change
Buyers 8 0.03 0.09 10,436
Sellers 11 -1.05 2.60 -307,434
Net -- -1.02 2.51 -296,998

Institutional Shareholder Concentration
  Values ($) % O/S Shares
Top 10 Inst. 17 58.79 6,957,079
Top 20 Inst. 17.29 60.20 7,123,899
Top 50 Inst. 17.35 60.40 7,146,736
Total Inst. 17.35 60.40 7,146,736

Institutional Shareholder Style
  Holders Values ($) % O/S Shares
Index 4 1 3.42 237,287
TotalGrowth 7 0 0.12 8,242
TotalOther 13 16 96.17 6,670,211
TotalValue 2 0 0.05 3,811
Yield 1 0 0.00 20

Top Holders: Institutional Investor
  Shares Held % O/S Shares Change Filing Date
Galen Partners 2,195,735 18.56 -20,964 02/01/2016
Essex Woodlands Health Ventures 1,956,357 16.53 -40 02/01/2016
Deerfield Management Company, L.P. 1,025,641 8.67 0 12/31/2015
Sabby Management, LLC 727,865 6.15 -15,738 12/31/2015
Care Capital, LLC 665,124 5.62 -196,784 03/09/2015
The Vanguard Group, Inc. 202,053 1.71 0 12/31/2015
Clemens (Peter A) 55,182 0.47 -723 02/01/2016
Renaissance Technologies LLC 52,820 0.45 4,000 12/31/2015
Emigh (James F) 39,660 0.34 -1 02/01/2016
Wesson (Bruce F) 36,642 0.31 10,306 02/01/2016
Highbridge Capital Management, LLC 27,114 0.23 -15,724 12/31/2015
Seiser (Robert A) 22,145 0.19 0 02/01/2016
Geode Capital Management, L.L.C. 21,045 0.18 42 12/31/2015
Financial Advisory Service, Inc 16,396 0.14 0 12/31/2015
Spark Investment Management LLC 15,755 0.13 -2,824 12/31/2015
Skelly (William G) 15,129 0.13 8,247 02/01/2016
Ross (George K) 13,280 0.11 10,523 02/01/2016
Northern Trust Investments, Inc. 12,805 0.11 0 12/31/2015
Jones (Robert B) 12,555 0.11 -1 02/01/2016
Thangaraj (Immanuel) 10,596 0.09 6,184 02/01/2016
Brzeczko (Albert W) 5,200 0.04 0 02/01/2016
Guggenheim Investments 3,711 0.03 412 03/31/2016
BlackRock Financial Management, Inc. 3,204 0.03 0 12/31/2015
Walleye Trading, LLC 2,732 0.02 1,532 12/31/2015
Group One Trading, L.P. 2,107 0.02 2,000 12/31/2015
Morgan Stanley Wealth Management 1,486 0.01 0 12/31/2015
BlackRock Institutional Trust Company, N.A. 1,384 0.01 1,384 12/31/2015
Atwood & Palmer Inc. 1,010 0.01 1,010 03/31/2016
Tower Research Capital LLC 736 0.01 -3,956 12/31/2015
Rivet (J Bradley) 400 0.00 0 02/01/2016
Manulife Asset Management Limited 389 0.00 0 12/31/2015
Bank of America Merrill Lynch (US) 240 0.00 0 12/31/2015
Creative Planning, Inc. 100 0.00 0 03/31/2016
Citi Investment Research (US) 56 0.00 56 12/31/2015
Northern Trust Global Investments Ltd. 40 0.00 0 12/31/2015
Morgan Stanley & Co. LLC 36 0.00 -2,528 12/31/2015
Thompson, Davis & Co., Inc. (Asset Management) 6 0.00 0 03/31/2016

Ownership data is provided by Thomson Reuters, a third party service, and Acura Pharmaceuticals, Inc. does not maintain or provide information directly to this service.