Ownership Profile

Shareholder Breakdown
  Holders Values ($) % O/S Shares
Institution 45 34.57 62.53 36,896,869
Mutual Fund 12 0.92 1.94 1,141,920

Institutional Shareholder Rotation
  Holders Values Change ($) % O/S Shares Change
Buyers 17 8.12 17.25 10,180,418
Sellers 16 -0.68 1.24 -728,886
Net -- 7.44 16.02 9,451,532

Institutional Shareholder Concentration
  Values ($) % O/S Shares
Top 10 Inst. 34 60.94 35,959,448
Top 20 Inst. 34.34 62.13 36,660,673
Top 50 Inst. 34.57 62.53 36,896,869
Total Inst. 34.57 62.53 36,896,869

Institutional Shareholder Style
  Holders Values ($) % O/S Shares
Index 5 1 3.39 1,219,782
CoreGrowth 6 0 0.11 39,372
Growth 1 0 0.00 32
VCPrivateEquity 3 24 67.45 24,291,104
HedgeFund 6 8 28.51 10,266,284
BrokerDealer 7 0 0.12 43,248
GARP 1 0 0.03 11,000
DeepValue 1 0 0.06 21,550
CoreValue 1 0 0.01 5,117
IncomeValue 2 0 0.10 34,751

Top Holders: Institutional Investor
  Shares Held % O/S Shares Change Filing Date
Galen Partners 11,083,497 18.78 0 06/01/2015
Essex Woodlands Health Ventures 9,871,985 16.73 -412,901 06/30/2015
Deerfield Management Company, L.P. 5,128,205 8.69 5,128,205 07/07/2015
Sabby Management, LLC 4,661,795 7.90 4,661,795 07/01/2015
Care Capital, LLC 3,335,622 5.65 10,000 06/01/2015
The Vanguard Group, Inc. 980,433 1.66 47,369 06/30/2015
Clemens (Peter A) 279,523 0.47 0 06/01/2015
Jacobs Levy Equity Management, Inc. 242,384 0.41 202,684 06/30/2015
Emigh (James F) 198,304 0.34 0 06/01/2015
Renaissance Technologies LLC 177,700 0.30 48,800 06/30/2015
Wesson (Bruce F) 131,678 0.22 0 06/01/2015
Seiser (Robert A) 110,725 0.19 0 06/01/2015
Geode Capital Management, L.L.C. 104,810 0.18 107 06/30/2015
Financial Advisory Service, Inc 81,983 0.14 0 06/30/2015
Northern Trust Investments, Inc. 68,300 0.12 -10,511 06/30/2015
Jones (Robert B) 62,778 0.11 0 06/01/2015
California Public Employees' Retirement System 45,339 0.08 0 06/30/2015
Spark Investment Management LLC 35,200 0.06 35,200 06/30/2015
Skelly (William G) 34,412 0.06 0 06/01/2015
Brzeczko (Albert W) 26,000 0.04 0 06/01/2015
INTRUST Bank, N.A. 23,960 0.04 0 06/30/2015
Thangaraj (Immanuel) 22,059 0.04 0 06/01/2015
Cortland Associates, Inc. 21,550 0.04 0 06/30/2015
Lincoln Capital, LLC 21,000 0.04 0 06/30/2015
Charles Schwab Investment Management, Inc. 20,900 0.04 0 06/30/2015
BlackRock Financial Management, Inc. 16,021 0.03 4,431 06/30/2015
Ross (George K) 13,784 0.02 0 06/01/2015
KCG Americas LLC 13,559 0.02 -5,847 06/30/2015
Commonwealth Financial Network 13,232 0.02 0 06/30/2015
Goldman Sachs & Company, Inc. 11,184 0.02 11,184 06/30/2015
Mariner Wealth Advisors, LLC 11,000 0.02 -20,000 06/30/2015
BNY Mellon Asset Management 10,791 0.02 10,791 06/30/2015
Susquehanna Financial Group, LLLP 10,258 0.02 10,258 06/30/2015
Morgan Stanley Wealth Management 7,430 0.01 140 06/30/2015
UBS Securities LLC 5,481 0.01 3,835 06/30/2015
AXA Rosenberg Investment Management LLC 5,117 0.01 5,117 01/31/2015
Bank of America Merrill Lynch (US) 2,100 0.00 0 06/30/2015
Rivet (J Bradley) 2,000 0.00 0 06/01/2015
Manulife Asset Management Limited 1,950 0.00 0 03/31/2015
John Hancock Advisers LLC 1,383 0.00 0 07/31/2015
Group One Trading, L.P. 539 0.00 -137 06/30/2015
Simplex Trading, LLC 500 0.00 500 06/30/2015
Northern Trust Global Investments Ltd. 200 0.00 0 06/30/2015
Morgan Stanley & Co. LLC 166 0.00 2 06/30/2015
Thompson, Davis & Co., Inc. (Asset Management) 32 0.00 0 06/30/2015

Ownership data is provided by Thomson Reuters, a third party service, and Acura Pharmaceuticals, Inc. does not maintain or provide information directly to this service.