Ownership Profile

Shareholder Breakdown
  Holders Values ($) % O/S Shares
Institution 35 24.86 61.28 7,231,374
Mutual Fund 13 0.58 1.96 231,702

Institutional Shareholder Rotation
  Holders Values Change ($) % O/S Shares Change
Buyers 13 2.62 9.44 1,113,406
Sellers 20 -0.18 0.65 -76,544
Net -- 2.44 8.79 1,036,862

Institutional Shareholder Concentration
  Values ($) % O/S Shares
Top 10 Inst. 24 59.26 6,992,100
Top 20 Inst. 24.77 61.00 7,197,850
Top 50 Inst. 24.86 61.28 7,231,374
Total Inst. 24.86 61.28 7,231,374

Institutional Shareholder Style
  Holders Values ($) % O/S Shares
Index 3 1 3.36 235,861
TotalGrowth 6 0 0.07 5,232
TotalOther 13 23 96.28 6,761,417
TotalValue 2 0 0.05 3,399
Yield 1 0 0.00 20

Top Holders: Institutional Investor
  Shares Held % O/S Shares Change Filing Date
Galen Partners 2,216,699 18.79 0 06/01/2015
Essex Woodlands Health Ventures 1,956,397 16.58 -18,000 09/30/2015
Deerfield Management Company, L.P. 1,025,641 8.69 1,025,641 09/30/2015
Sabby Management, LLC 727,867 6.17 -15,736 12/31/2015
Care Capital, LLC 667,124 5.65 2,000 06/01/2015
The Vanguard Group, Inc. 202,053 1.71 5,966 09/30/2015
Clemens (Peter A) 55,905 0.47 0 06/01/2015
Renaissance Technologies LLC 48,820 0.41 13,280 09/30/2015
Jacobs Levy Equity Management, Inc. 48,756 0.41 279 09/30/2015
Highbridge Capital Management, LLC 42,838 0.36 42,838 09/30/2015
Emigh (James F) 39,661 0.34 0 06/01/2015
Wesson (Bruce F) 36,645 0.31 10,309 01/04/2016
Seiser (Robert A) 22,145 0.19 0 06/01/2015
Geode Capital Management, L.L.C. 21,003 0.18 41 09/30/2015
Spark Investment Management LLC 18,579 0.16 11,539 09/30/2015
Financial Advisory Service, Inc 16,396 0.14 0 12/31/2015
Skelly (William G) 15,129 0.13 8,247 01/04/2016
Northern Trust Investments, Inc. 12,805 0.11 -855 09/30/2015
Jones (Robert B) 12,556 0.11 0 06/01/2015
Ross (George K) 10,831 0.09 8,074 01/04/2016
Thangaraj (Immanuel) 10,597 0.09 6,185 01/04/2016
Brzeczko (Albert W) 5,200 0.04 0 06/01/2015
Tower Research Capital LLC 4,692 0.04 4,692 09/30/2015
Guggenheim Investments 3,299 0.03 3,299 12/31/2015
BlackRock Financial Management, Inc. 3,204 0.03 0 09/30/2015
Morgan Stanley & Co. LLC 2,564 0.02 2,531 09/30/2015
Morgan Stanley Wealth Management 1,486 0.01 0 09/30/2015
Walleye Trading, LLC 1,200 0.01 1,200 09/30/2015
Rivet (J Bradley) 400 0.00 0 06/01/2015
Manulife Asset Management Limited 389 0.00 -1 09/30/2015
Bank of America Merrill Lynch (US) 240 0.00 -180 09/30/2015
Group One Trading, L.P. 107 0.00 -1 09/30/2015
Creative Planning, Inc. 100 0.00 100 12/31/2015
Northern Trust Global Investments Ltd. 40 0.00 0 09/30/2015
Thompson, Davis & Co., Inc. (Asset Management) 6 0.00 0 12/31/2015

Ownership data is provided by Thomson Reuters, a third party service, and Acura Pharmaceuticals, Inc. does not maintain or provide information directly to this service.