Attention:
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Jeffrey
Riedler, Mail Stop 6010
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Assistant
Director, Division of Corporate
Finance
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Re:
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Acceleration
Request for
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Acura
Pharmaceuticals, Inc.
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Registration
Statement on Form S-3
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File
No. 333-146416 Filed October 1, 2007
and
as Amended on November 14,
2007
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•
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should
the Commission or the staff, acting pursuant to delegated authority,
declare the filing effective, it does not foreclose the Commission
from
taking any action with respect to the filing;
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•
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the
action of the Commission or the staff, acting pursuant to delegated
authority, in declaring the filing effective, does not relieve Acura
Pharmaceuticals, Inc. from its full responsibility for the adequacy
and
accuracy of the disclosures in the filing; and
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•
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Acura
Pharmaceuticals, Inc. may not assert this action as a defense in
any
proceeding by the Commission or any person under the federal securities
laws of the United States.
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By:
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s/
Peter A. Clemens
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Name:
Peter A. Clemens
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Senior
Vice President and
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Chief
Financial Officer
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