Accounts Payable And Accrued Liabilities Disclosure [Text Block] ACCRUED EXPENSES Accounts Payable and Accrued Liabilities [Line Items] Accounts Payable And Accrued Liabilities [Line Items] Accounts Payable and Accrued Liabilities [Line Items] Accounts Payable and Accrued Liabilities [Table] Accounts Payable And Accrued Liabilities [Table] Accounts Payable and Accrued Liabilities [Table] Accounts Payable Current Accounts payable Accrual For Taxes Other Than Income Taxes Current Property taxes Accrued Liabilities Current Accrued expenses Total Accrued Other Professional Fees, Current Accrued Other Professional Fees Current Clinical and regulatory services Accrued Professional Fees Current Professional services Accrued Research and Development Expense, Current Accrued Research And Development Expense Current Accrued research and development expense Additional Paid In Capital Common Stock Additional paid-in capital Additional Paid In Capital [Member] Additional Paid-in Capital Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition, Shares Adjustments To Additional Paid In Capital Share Based Compensation Requisite Service Period Recognition Shares Share-based compensation (in shares) Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value Share-based compensation Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract] Adjustments to reconcile net (loss) income to net cash (used in) provided by operating activities: Amendment Flag Amendment Flag Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount Excluded potentially dilutive securities Potentially dilutive securities excluded from diluted earnings (loss) per share computation Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis] Antidilutive Securities [Axis] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Name [Domain] Antidilutive Securities, Name [Domain] Assets Total assets Assets [Abstract] Assets Assets Current Total current assets Assets Current [Abstract] Current assets Award Type [Axis] Award Type [Axis] California State [Member] California State [Member] California State Cash And Cash Equivalents At Carrying Value Cash and cash equivalents at end of period Cash and cash equivalents at beginning of period Cash and cash equivalents Cash And Cash Equivalents Period Increase Decrease Net decrease in cash and cash equivalents Cash Flow Noncash Investing And Financing Activities Disclosure [Abstract] Supplemental Disclosure of Noncash Financing Activities: Cash Paid During Period For [Abstract] Cash Paid During Period For [Abstract] Cash paid for: Class of Warrant or Right, Expiration Date Class Of Warrant Or Right Expiration Date Common stock Warrant expiration date Class Of Warrant Or Right [Line Items] Class of Warrant or Right [Line Items] Class Of Warrant Or Right Outstanding Common stock warrant exercisable outstanding, shares Class Of Warrant Or Right [Table] Class of Warrant or Right [Table] Commitments And Contingencies Commitments and contingencies (Note 9) Commitments and Contingencies Disclosure [Line Items] Commitments And Contingencies Disclosure [Line Items] Commitments and Contingencies Disclosure [Line Items] Commitments and Contingencies Disclosure [Table] Commitments And Contingencies Disclosure [Table] Commitments and Contingencies Disclosure [Table] Commitments And Contingencies Disclosure [Text Block] COMMITMENTS AND CONTINGENCIES Common Stock Issued, Shares Common Stock Issued Shares Common Stock issued upon exercise Common Stock [Member] Common Stock Common Stock Par Or Stated Value Per Share Common stock, par value Common Stock Shares Authorized Common stock, shares authorized Common Stock Shares Issued Common stock, shares issued Common Stock Shares Outstanding Common stock, shares outstanding Common Stock Value Common stock - $.01 par value; 100,000 shares authorized; 45,864 and 45,320 shares issued and outstanding at June 30, 2012 and December 31, 2011 Common Stock Withheld , Shares Common Stock Withheld Shares Common stock withheld in exercise costs in shares Costs And Expenses Total operating expenses Costs And Expenses [Abstract] Operating expenses Current Fiscal Year End Date Current Fiscal Year End Date Deferred Revenue Arrangement By Type [Table] Deferred Revenue Arrangement, by Type [Table] Deferred Revenue Arrangement [Line Items] Deferred Revenue Arrangement [Line Items] Deferred Revenue Arrangement Type [Axis] Deferred Revenue Arrangement Type [Axis] Deferred Revenue Arrangement Type [Domain] Deferred Revenue Arrangement Type [Domain] Deferred Revenue Current Deferred program fee revenue Depreciation Depreciation Disclosure - Accrued Expenses [Abstract] Disclosure Accrued Expenses [Abstract] Disclosure - Accrued Expenses [Abstract] Disclosure - Assumptions Used in Black-Scholes Model to Determine Fair Value for Stock Option Awards Granted [Abstract] Disclosure Assumptions Used In Black Scholes Model To Determine Fair Value For Stock Option Awards Granted [Abstract] Disclosure - Assumptions Used in Black-Scholes Model to Determine Fair Value for Stock Option Awards Granted [Abstract] Disclosure - Commitments and Contingencies - Additional Information [Abstract] Disclosure Commitments And Contingencies Additional Information [Abstract] Disclosure - Commitments and Contingencies - Additional Information [Abstract] Disclosure - Common Stock Warrants - Additional Information [Abstract] Disclosure Common Stock Warrants Additional Information [Abstract] Disclosure - Common Stock Warrants - Additional Information [Abstract] Disclosure - Computation of Basic and Diluted Earnings (Loss) Per Share [Abstract] Disclosure Computation Of Basic And Diluted Earnings Loss Per Share [Abstract] Disclosure - Computation of Basic and Diluted Earnings (Loss) Per Share [Abstract] Disclosure - Earnings (Loss) Per Share - Additional Information [Abstract] Disclosure Earnings Loss Per Share Additional Information [Abstract] Disclosure - Earnings (Loss) Per Share - Additional Information [Abstract] Disclosure - Non-Cash Share-Based Compensation Expense [Abstract] Disclosure Non Cash Share Based Compensation Expense [Abstract] Disclosure - Non-Cash Share-Based Compensation Expense [Abstract] Disclosure Of Compensation Related Costs Share Based Payments [Text Block] SHARE-BASED COMPENSATION Disclosure - Research and Development - Additional Information [Abstract] Disclosure Research And Development Additional Information [Abstract] Disclosure - Research and Development - Additional Information [Abstract] Disclosure - Revenue Recognition and Deferred Program Fee Revenue - Additional Information [Abstract] Disclosure Revenue Recognition And Deferred Program Fee Revenue Additional Information [Abstract] Disclosure - Revenue Recognition and Deferred Program Fee Revenue - Additional Information [Abstract] Disclosure - Share-Based Compensation - Additional Information [Abstract] Disclosure Share Based Compensation Additional Information [Abstract] Disclosure - Share-Based Compensation - Additional Information [Abstract] Disclosure - Stock Option Award Activity [Abstract] Disclosure Stock Option Award Activity [Abstract] Disclosure - Stock Option Award Activity [Abstract] Disclosure - Summary of Restricted Stock Units Plan [Abstract] Disclosure Summary Of Restricted Stock Units Plan [Abstract] Disclosure - Summary of Restricted Stock Units Plan [Abstract] Document - Document and Entity Information [Abstract] Document Documentand Entity Information [Abstract] Document - Document and Entity Information [Abstract] Document Fiscal Period Focus Document Fiscal Period Focus Document Fiscal Year Focus Document Fiscal Year Focus Document Information [Line Items] Document Information [Line Items] Document Period End Date Document Period End Date Document Type Document Type Earning Per Share, Basic Numerator [Abstract] Earning Per Share Basic Numerator [Abstract] Numerator: Earnings Per Share [Abstract] Income (loss) per share Earnings Per Share Basic Basic Basic income (loss) per common share Earnings Per Share Basic [Abstract] Basic income (loss) per share computation Earnings Per Share Diluted Diluted Diluted income (loss) per common share Earnings Per Share Diluted [Abstract] Diluted income per share computation Earnings Per Share Diluted Numerator [Abstract] Earnings Per Share Diluted Numerator [Abstract] Numerator: Earnings Per Share Disclosure [Line Items] Earnings Per Share Disclosure [Line Items] Earnings Per Share Disclosure [Line Items] Earnings Per Share Disclosure [Table] Earnings Per Share Disclosure [Table] Earnings Per Share Disclosure [Table] Earnings Per Share [Text Block] EARNINGS (LOSS) PER SHARE Employee Related Liabilities Current Payroll, payroll taxes, bonus and benefits Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Unrecognized share based compensation Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition 1 Unrecognized share based compensation, recognition period Entities [Table] Entities [Table] Entity Central Index Key Entity Central Index Key Entity Common Stock Shares Outstanding Entity Common Stock, Shares Outstanding Entity [Domain] Entity [Domain] Entity Filer Category Entity Filer Category Entity Registrant Name Entity Registrant Name Equity Based Employee Compensation Granted, Shares Equity Based Employee Compensation Granted Shares Equity based employee compensation granted Equity Component [Domain] Equity Component [Domain] Equity Issuance Costs Withheld Equity Issuance Costs Withheld Common stock withheld in exercise costs Exercise Price Of Warrants Exercise Price Of Warrants Common stock warrant exercise price Gain Loss On Sale Of Property Plant Equipment Loss on disposal of property and equipment General And Administrative Expense [Member] General and administrative Income Loss From Continuing Operations Before Income Taxes Minority Interest And Income Loss From Equity Method Investments Income (loss) before income tax Income Statement [Abstract] Income Statement [Abstract] Income Tax Disclosure [Text Block] INCOME TAXES Income Taxes Paid Income taxes Income Taxes Receivable Income taxes refundable Income Tax Expense Benefit Income tax expense Increase Decrease In Accounts Payable Accounts payable Increase Decrease In Accrued Income Taxes Payable Income taxes payable Increase Decrease In Accrued Liabilities Accrued expenses Increase Decrease In Deferred Revenue Deferred program fee revenue Increase Decrease In Operating Capital [Abstract] Changes in operating assets and liabilities: Increase Decrease In Prepaid Deferred Expense And Other Assets Prepaid expenses and other current assets Increase Decrease In Receivables Collaboration revenue receivable Incremental Common Shares Attributable To Call Options And Warrants Common stock warrants Incremental Common Shares Attributable To Share Based Payment Arrangements Common stock options Interest Paid Interest Interim Period Costs Not Allocable [Domain] Interim Period, Costs Not Allocable [Domain] Legal Entity [Axis] Legal Entity [Axis] Liabilities And Stockholders Equity Total liabilities and stockholders' equity Liabilities And Stockholders Equity [Abstract] Liabilities and Stockholders' Equity Liabilities Current Total current liabilities Liabilities Current [Abstract] Current liabilities License Fees [Member] License Fees [Member] License Fees Location [Axis] Location [Axis] Location [Axis] Locations [Domain] Locations [Domain] Locations [Domain] Loss Contingency Number Of Plaintiffs Number of plaintiffs served in a single complaint Nature Of Expense [Axis] Nature of Expense [Axis] Net Cash Provided By Used In Financing Activities Net cash used in finance activities Net Cash Provided By Used In Financing Activities [Abstract] Cash flows used in financing activities: Net Cash Provided By Used In Operating Activities Net cash (used in) provided operating activities Net Cash Provided By Used In Operating Activities [Abstract] Cash flows used in operatin-g activities: Net Income Loss Net loss Net (loss) income Net income (loss) Net income (loss) New Jersey State [Member] New Jersey State [Member] New Jersey State Number of Lawsuits Filed Number Of Lawsuits Filed Number of lawsuits filed Number of Lawsuits Served Number Of Lawsuits Served Number of lawsuits served Number Of Stock Incentive Plans Number Of Stock Incentive Plans Number of stock options plans Operating Income Loss Income (loss) from operations Operating Revenue Disclosure. Operating Revenue Disclosure [Text Block] REVENUE RECOGNITION AND DEFERRED PROGRAM FEE REVENUE Option Non Cash Exercise1 [Member] Option Non Cash Exercise One [Member] Cashless exercise of stock options Organization Consolidation And Presentation Of Financial Statements Disclosure [Text Block] BASIS OF PRESENTATION Other Accrued Liabilities Current Other fees and services Other Accrued Taxes Current Other Accrued Taxes Current Franchise taxes Other Nonoperating Income Expense Other income (expense), net Payments Related To Tax Withholding For Share Based Compensation Statutory minimum withholding taxes paid on the distribution of common stock pursuant to restricted stock unit plan and exercise of stock options Payments To Acquire Property Plant And Equipment Cash flows used in investing activities - purchase of property and equipment Pennsylvania State [Member] Pennsylvania State [Member] Pennsylvania State Prepaid Expense And Other Assets Current Prepaid expenses and other current assets Prepaid Insurance Prepaid insurance Proceeds From Other Equity Distribution of restricted stock units Proceeds From Stock Options Exercised Exercise of stock options Proceeds From Warrant Exercises Net proceeds from warrant exercise Program fee revenue Program Fee Revenue Program fee revenue Property Plant And Equipment Net Property, plant and equipment, net Research And Development Assets Acquired Other Than Through Business Combination [Line Items] Research and Development Assets Acquired Other than Through Business Combination [Line Items] Research And Development Disclosure. Research And Development Disclosure [Text Block] RESEARCH AND DEVELOPMENT Research And Development Expense Research and development Research And Development Expense [Member] Research and development Restricted Stock Shares Issued Net Of Shares For Tax Withholdings Restricted stock units distributed net of shares for tax withholdings Restricted Stock Unit [Member] Restricted Stock Unit [Member] Restricted Stock Units (RSUs) Restricted Stock Units R S U [Member] Restricted Stock Units (RSUs) Retained Earnings Accumulated Deficit Accumulated deficit Retained Earnings [Member] Accumulated Deficit Revenue Recognition Milestone Method Revenue Recognized Milestone revenue Revenues Total revenues Revenues [Abstract] Revenues Scenario Unspecified [Domain] Scenario, Unspecified [Domain] Schedule Of Accrued Liabilities Table [Text Block] Accrued Expenses Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Schedule Of Earnings Per Share Basic And Diluted Table [Text Block] Computation of Basic and Diluted Earnings (Loss) Per Share Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block] Non-Cash Share-Based Compensation Expense Schedule Of Research And Development Assets Acquired Other Than Through Business Combination [Table] Schedule of Research and Development Assets Acquired Other than Through Business Combination [Table] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule Of Share Based Compensation Restricted Stock Units Award Activity Table [Text Block] Summary of Restricted Stock Units Plan Schedule Of Share Based Compensation Stock Options Activity Table [Text Block] Stock Option Award Activity Schedule Of Share Based Payment Award Stock Options Valuation Assumptions Table [Text Block] Assumptions Used in Black-Scholes Model to Determine Fair Value for Stock Option Awards Granted Selling General And Administrative Expense Marketing, general and administrative Share Based Compensation Non-cash share-based compensation expense Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Option, Awards Distributed Percentage Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Option Awards Distributed Percentage Vested shares distributed percentage to date Share Based Compensation Arrangement by Share Based Payment Award, Equity Instruments Other Than Options, Distributed in Period Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Distributed In Period Restricted stock units distributed Distributed Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited In Period Forfeited or expired Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Granted Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number Outstanding, ending Outstanding, beginning Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Vested Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate Dividend yield Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Forfeitures Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Forfeitures Expected forfeitures Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term 1 Expected holding period Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Average volatility Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Average risk-free interest rate Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number Number of options exercisable Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price Weighted average exercise price, options exercisable Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period Number of options, forfeited or expired Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Number of options, granted Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value Weighted average grant date fair value Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number Number of options outstanding, ending Number of options outstanding, beginning Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price Weighted average exercise price, ending Weighted average exercise price, beginning Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain] Award Type [Domain] Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price Weighted average exercise price, exercised Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price Weighted average exercise price, forfeited or expired Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price Weighted average exercise price, granted Shares Outstanding Ending Balance (in shares) Beginning Balance (in shares) Shares Paid For Tax Withholding For Share Based Compensation Shares withheld Shares withheld for tax, shares Shares Withheld For Tax Shares Common shares withheld for withholding taxes (in shares) Shares withheld for tax, value Shares Withheld For Tax Value Common shares withheld for withholding taxes Shares Withheld to Satisfy Employees Tax Withholding, Shares Shares Withheld To Satisfy Employees Tax Withholding Shares Witholding of exercise cost in shares Statement Equity Components [Axis] Equity Components [Axis] Statement [Line Items] Statement [Line Items] Statement Of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Statement Of Financial Position [Abstract] Statement of Financial Position [Abstract] Statement Of Stockholders Equity [Abstract] Statement of Stockholders' Equity [Abstract] Statement Scenario [Axis] Scenario [Axis] Statement [Table] Statement [Table] Stockholders Equity Ending Balance Beginning Balance Total stockholders' equity Stockholders Equity [Abstract] Stockholders' equity Stockholders Equity Note Disclosure [Text Block] COMMON STOCK WARRANTS Stock Issued During Period Shares Restricted Stock Award Net Of Forfeitures Net distribution of common stock pursuant to restricted stock unit award plan (in shares) Stock Issued During Period Shares Stock Options Exercised Issuance of common stock for exercise of stock options (in shares) Options exercised to purchase common stock, shares Number of options, exercised Stock Issued During Period Shares Stock Options Exercised, Net of Shares for Tax Withholdings Stock Issued During Period Shares Stock Options Exercised Net Of Shares For Tax Withholdings Options exercised to purchase common stock net of shares for tax withholdings Stock Issued During Period Value Restricted Stock Award Net Of Forfeitures Net distribution of common stock pursuant to restricted stock unit award plan Stock Issued During Period Value Stock Options Exercised Issuance of common stock for exercise of stock options Stock Option [Member] Stock Option Stock Options [Member] Stock options Supplemental Cash Flow Information [Abstract] Supplemental cash flow information Supplemental Tax Withholding Supplemental Tax Withholding Minimum statutory withholding payroll taxes withheld Taxes withheld on issuance of stock-based awards. Taxes Withheld On Issuance Of Stock Based Awards Shares withheld, value Text Block [Abstract] Text Block [Abstract] Trading Symbol Trading Symbol Up Front Payment Arrangement [Member] Up-front Payments Arrangement Vested Restricted Stock Units [Member] Vested Restricted Stock Units [Member] Vested Restricted Stock Units (RSUs) Warrant [Member] Common stock warrants Weighted Average Number Of Diluted Shares Outstanding Diluted Weighted average number of shares outstanding Weighted Average Number Of Shares Issued Basic Common shares (weighted) Weighted Average Number Of Shares Outstanding Basic Basic Weighted average number of shares outstanding Weighted Average Number Of Shares Outstanding Basic [Abstract] Denominator: Weighted Average Number Of Shares Outstanding Diluted Disclosure Items [Abstract] Denominator: Weighted average shares Weighted Average Number Of Shares Restricted Stock Vested RSUs (weighted)